Blood flow dynamics after laser therapy of port wine stain birthmarks

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Blood flow dynamics after laser therapy of port wine stain birthmarks.

BACKGROUND AND OBJECTIVE During laser therapy of port wine stain (PWS) birthmarks, regions of perfusion may persist. We hypothesize that such regions are not readily observable even when laser surgery is performed by highly experienced clinicians. The objective of this study was to use objective feedback to assess the acute vascular response to laser therapy. STUDY DESIGN/MATERIALS AND METHOD...

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Noninvasive blood flow imaging for real-time feedback during laser therapy of port wine stain birthmarks.

BACKGROUND AND OBJECTIVES During laser therapy of port wine stain (PWS) birthmarks, regions of persistent perfusion may exist. Immediate retreatment of such regions may improve PWS laser therapeutic outcome. To address this need, we propose use of laser speckle imaging (LSI) to provide real-time, quantitative feedback during laser surgery. Herein, we present in vitro and in vivo data collected ...

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Intraoperative, real-time monitoring of blood flow dynamics associated with laser surgery of port wine stain birthmarks.

BACKGROUND AND OBJECTIVE Port-wine stain (PWS) birthmarks affect ∼22 million people worldwide. After several treatment sessions, complete disappearance of the PWS occurs in only ∼10% of treated patients. There is a need to develop a new strategy to improve the efficacy of each treatment session and the overall treatment outcome. The study objective was to determine how intraoperative measuremen...

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Combined benzoporphyrin derivative monoacid ring photodynamic therapy and pulsed dye laser for port wine stain birthmarks.

BACKGROUND Pulsed dye laser (PDL) is a commonly utilized treatment for port wine stain birthmarks (PWS) in the United States; however, results are variable and few patients achieve complete removal. Photodynamic therapy (PDT) is commonly used in China, but treatment associated photosensitivity lasts several weeks and scarring may occur. We propose an alternative treatment option, combined PDT+P...

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Description and analysis of treatments for port-wine stain birthmarks.

Port-wine stain (PWS) birthmarks are congenital, low-flow vascular malformations of the skin. Lasers are the modality of choice for the treatment of PWS birthmarks, and for most patients the pulsed-dye laser in conjunction with epidermal cooling offers the greatest efficacy and safety. Other light devices, including the 532-nm frequency-doubled Nd:YAG laser, intense pulsed light, 1064-nm Nd:YAG...

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ژورنال

عنوان ژورنال: Lasers in Surgery and Medicine

سال: 2009

ISSN: 0196-8092

DOI: 10.1002/lsm.20840